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Prognostic impact of circulating tumor cell apoptosis and clusters in serial blood samples from patients with metastatic breast cancer in a prospective observational cohort

BACKGROUND: Presence of circulating tumor cells (CTCs) is a validated prognostic marker in metastatic breast cancer. Additional prognostic information may be obtained by morphologic characterization of CTCs. We explored whether apoptotic CTCs, CTC clusters and leukocytes attached to CTCs are associa...

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Detalles Bibliográficos
Autores principales: Jansson, Sara, Bendahl, Pär-Ola, Larsson, Anna-Maria, Aaltonen, Kristina E., Rydén, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938919/
https://www.ncbi.nlm.nih.gov/pubmed/27390845
http://dx.doi.org/10.1186/s12885-016-2406-y