Cargando…
The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity
BACKGROUND: The ability to capture and sequence large contiguous DNA fragments represents a significant advancement towards the comprehensive characterization of complex genomic regions. While emerging sequencing platforms are capable of producing several kilobases-long reads, the fragment sizes gen...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938946/ https://www.ncbi.nlm.nih.gov/pubmed/27393338 http://dx.doi.org/10.1186/s12864-016-2836-6 |