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The next generation of target capture technologies - large DNA fragment enrichment and sequencing determines regional genomic variation of high complexity
BACKGROUND: The ability to capture and sequence large contiguous DNA fragments represents a significant advancement towards the comprehensive characterization of complex genomic regions. While emerging sequencing platforms are capable of producing several kilobases-long reads, the fragment sizes gen...
Autores principales: | Dapprich, Johannes, Ferriola, Deborah, Mackiewicz, Kate, Clark, Peter M., Rappaport, Eric, D’Arcy, Monica, Sasson, Ariella, Gai, Xiaowu, Schug, Jonathan, Kaestner, Klaus H., Monos, Dimitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938946/ https://www.ncbi.nlm.nih.gov/pubmed/27393338 http://dx.doi.org/10.1186/s12864-016-2836-6 |
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