Gas1 up-regulation is inducible and contributes to cell apoptosis in reactive astrocytes in the substantia nigra of LPS and MPTP models

BACKGROUND: Reactive astrogliosis is a remarkable pathogenetic hallmark of the brains of Parkinson’s disease (PD) patients, but its progressive fate and regulation mechanisms are poorly understood. In this study, growth arrest specific 1 (Gas1), a tumor growth suppressor oncogene, was identified as...

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Detalles Bibliográficos
Autores principales: Sun, Xiao-Long, Chen, Bei-Yu, Zhao, Hai-Kang, Cheng, Ying-Ying, Zheng, Min-Hua, Duan, Li, Jiang, Wen, Chen, Liang-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938987/
https://www.ncbi.nlm.nih.gov/pubmed/27391369
http://dx.doi.org/10.1186/s12974-016-0643-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938987/
https://www.ncbi.nlm.nih.gov/pubmed/27391369
http://dx.doi.org/10.1186/s12974-016-0643-2

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