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Involvement of DNMT 3B promotes epithelial-mesenchymal transition and gene expression profile of invasive head and neck squamous cell carcinomas cell lines

BACKGROUND: The 5-year overall survival rates for head and neck cancer (HNC) relies on distant metastasis. Importantly, the epithelial-mesenchymal transition (EMT) is believed to be an initial step of metastasis. However, the relationship of epigenetic with EMT formation is still unexplored in HNC....

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Detalles Bibliográficos
Autores principales: Chen, Li-Hsuen, Hsu, Wen-Lin, Tseng, Yen-Ju, Liu, Dai-Wei, Weng, Ching-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938990/
https://www.ncbi.nlm.nih.gov/pubmed/27391030
http://dx.doi.org/10.1186/s12885-016-2468-x