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Efficacy of delayed treatment of China-made Peramivir with repeated intravenous injections in a mouse influenza model: from clinical experience to basal experiment

BACKGROUND: China-made Peramivir, an anti-influenza neuraminidase inhibitor drug, is manufactured and widely used in China. Although effective if initiated within 48 h of the onset of symptoms, yet we observed that this drug shows an inconclusive efficacy if treatment is delayed in clinical. Thus we...

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Detalles Bibliográficos
Autores principales: Li, Zhengtu, Li, Runfeng, Li, Jing, Xie, Hui, Hao, Yanbing, Du, Qiuling, Chen, Tingting, Li, Yimin, Chen, Rongchang, Yang, Zifeng, Zhong, Nanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939023/
https://www.ncbi.nlm.nih.gov/pubmed/27392915
http://dx.doi.org/10.1186/s12879-016-1589-9