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The dynamic interactome and genomic targets of Polycomb complexes during stem cell differentiation

While the core subunits of Polycomb group (PcG) complexes are well characterized, little is known about the dynamics of these protein complexes during cellular differentiation. We used quantitative interaction proteomics and genome-wide profiling to study PcG proteins in mouse embryonic stem cells (...

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Detalles Bibliográficos
Autores principales: Kloet, Susan L., Makowski, Matthew M., Baymaz, H. Irem, van Voorthuijsen, Lisa, Karemaker, Ino D., Santanach, Alexandra, Jansen, Pascal W.T.C., Di Croce, Luciano, Vermeulen, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939079/
https://www.ncbi.nlm.nih.gov/pubmed/27294783
http://dx.doi.org/10.1038/nsmb.3248