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Acute selective serotonin reuptake inhibitors regulate the dorsal raphe nucleus causing amplification of terminal serotonin release

Selective serotonin reuptake inhibitors (SSRIs) were designed to treat depression by increasing serotonin levels throughout the brain via inhibition of clearance from the extracellular space. Although increases in serotonin levels are observed after acute SSRI exposure, 3–6 weeks of continuous use i...

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Detalles Bibliográficos
Autores principales: Dankoski, Elyse C., Carroll, Susan, Wightman, Robert Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939133/
https://www.ncbi.nlm.nih.gov/pubmed/26749030
http://dx.doi.org/10.1111/jnc.13528