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Mitochondrial unfolded protein response controls matrix pre-RNA processing and translation

The mitochondrial matrix is unique in that it must integrate folding and assembly of proteins derived from nuclear and mitochondrial genomes. In C. elegans, the mitochondrial unfolded protein response (UPR(mt)) senses matrix protein misfolding and induces a program of nuclear gene expression, includ...

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Detalles Bibliográficos
Autores principales: Münch, Christian, Harper, J. Wade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939261/
https://www.ncbi.nlm.nih.gov/pubmed/27350246
http://dx.doi.org/10.1038/nature18302