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How large are the consequences of covariate imbalance in cluster randomized trials: a simulation study with a continuous outcome and a binary covariate at the cluster level

BACKGROUND: The number of clusters in a cluster randomized trial is often low. It is therefore likely random assignment of clusters to treatment conditions results in covariate imbalance. There are no studies that quantify the consequences of covariate imbalance in cluster randomized trials on param...

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Detalles Bibliográficos
Autores principales: Moerbeek, Mirjam, van Schie, Sander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939594/
https://www.ncbi.nlm.nih.gov/pubmed/27401771
http://dx.doi.org/10.1186/s12874-016-0182-7