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The biofilm inhibitor Carolacton inhibits planktonic growth of virulent pneumococci via a conserved target

New antibacterial compounds, preferentially exploiting novel cellular targets, are urgently needed to fight the increasing resistance of pathogens against conventional antibiotics. Here we demonstrate that Carolacton, a myxobacterial secondary metabolite previously shown to damage Streptococcus muta...

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Detalles Bibliográficos
Autores principales: Donner, Jannik, Reck, Michael, Bergmann, Simone, Kirschning, Andreas, Müller, Rolf, Wagner-Döbler, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939601/
https://www.ncbi.nlm.nih.gov/pubmed/27404808
http://dx.doi.org/10.1038/srep29677