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An Optimized Protocol for Packaging Pseudotyped Integrase Defective Lentivirus

BACKGROUND: A number of integrase defective lentiviral (IDLV) packaging systems have been developed to produce integration deficient lentiviruses for gene delivery and epichromosomal expression. However, despite their growing demand, a comparative study to systemically evaluate the performance effic...

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Detalles Bibliográficos
Autores principales: Sengupta, Ranjita, Mukherjee, Chandreyee, Sarkar, Nandita, Sun, Zhihong, Lesnik, Jacob, Huang, Joseph, Lu, Biao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939624/
https://www.ncbi.nlm.nih.gov/pubmed/27403084
http://dx.doi.org/10.1186/s12575-016-0044-z