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Developmental Programming: Prenatal Testosterone Excess and Insulin Signaling Disruptions in Female Sheep
Women with polycystic ovary syndrome often manifest insulin resistance. Using a sheep model of polycystic ovary syndrome-like phenotype, we explored the contribution of androgen and insulin in programming and maintaining disruptions in insulin signaling in metabolic tissues. Phosphorylation of AKT,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for the Study of Reproduction, Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939741/ https://www.ncbi.nlm.nih.gov/pubmed/27053365 http://dx.doi.org/10.1095/biolreprod.115.136283 |