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Developmental Programming: Prenatal Testosterone Excess and Insulin Signaling Disruptions in Female Sheep

Women with polycystic ovary syndrome often manifest insulin resistance. Using a sheep model of polycystic ovary syndrome-like phenotype, we explored the contribution of androgen and insulin in programming and maintaining disruptions in insulin signaling in metabolic tissues. Phosphorylation of AKT,...

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Detalles Bibliográficos
Autores principales:	Lu, Chunxia, Cardoso, Rodolfo C., Puttabyatappa, Muraly, Padmanabhan, Vasantha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for the Study of Reproduction, Inc. 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939741/ https://www.ncbi.nlm.nih.gov/pubmed/27053365 http://dx.doi.org/10.1095/biolreprod.115.136283

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