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1,25(OH)(2)D(3) Induces Placental Vascular Smooth Muscle Cell Relaxation by Phosphorylation of Myosin Phosphatase Target Subunit 1(Ser507): Potential Beneficial Effects of Vitamin D on Placental Vasculature in Humans

Placental vascular dysfunction has been linked to insufficiency/deficiency of maternal vitamin D levels during pregnancy. In contrast, sufficient maternal vitamin D levels have shown beneficial effects on pregnancy outcomes. To study the role of vitamin D in pregnancy, we tested our hypothesis that...

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Detalles Bibliográficos
Autores principales: Jia, Xiuyue, Gu, Yang, Groome, Lynn J., Al-Kofahi, Mahmoud, Alexander, J. Steven, Li, Weimin, Wang, Yuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for the Study of Reproduction, Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939743/
https://www.ncbi.nlm.nih.gov/pubmed/27075619
http://dx.doi.org/10.1095/biolreprod.116.138362