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Impaired mTORC2 signaling in catecholaminergic neurons exaggerates high fat diet-induced hyperphagia

OBJECTIVE: Food intake is highly regulated by central homeostatic and hedonic mechanisms in response to peripheral and environmental cues. Neutral energy balance stems from proper integration of homeostatic signals with those “sensing” the rewarding properties of food. Impairments in brain insulin s...

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Detalles Bibliográficos
Autores principales: Dadalko, Olga I., Niswender, Kevin, Galli, Aurelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939830/
https://www.ncbi.nlm.nih.gov/pubmed/27441217
http://dx.doi.org/10.1016/j.heliyon.2015.e00025