Cargando…
Impaired mTORC2 signaling in catecholaminergic neurons exaggerates high fat diet-induced hyperphagia
OBJECTIVE: Food intake is highly regulated by central homeostatic and hedonic mechanisms in response to peripheral and environmental cues. Neutral energy balance stems from proper integration of homeostatic signals with those “sensing” the rewarding properties of food. Impairments in brain insulin s...
Autores principales: | Dadalko, Olga I., Niswender, Kevin, Galli, Aurelio |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939830/ https://www.ncbi.nlm.nih.gov/pubmed/27441217 http://dx.doi.org/10.1016/j.heliyon.2015.e00025 |
Ejemplares similares
-
Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
por: Kosillo, Polina, et al.
Publicado: (2022) -
Stress- and diet-induced fat gain is controlled by NPY in catecholaminergic neurons
por: Zhang, Lei, et al.
Publicado: (2014) -
PNOC(ARC) Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding
por: Jais, Alexander, et al.
Publicado: (2020) -
mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016) -
Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission
por: McCabe, Matthew P, et al.
Publicado: (2020)