Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression

Half of human genome is made of repetitive DNA. However, mechanisms underlying replication of chromosome regions containing repetitive DNA are poorly understood. We reconstituted replication of defined human chromosome segments using Bacterial Artificial Chromosomes (BACs) in Xenopus laevis egg extr...

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Detalles Bibliográficos
Autores principales: Aze, Antoine, Sannino, Vincenzo, Soffientini, Paolo, Bachi, Angela, Costanzo, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939857/
https://www.ncbi.nlm.nih.gov/pubmed/27111843
http://dx.doi.org/10.1038/ncb3344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939857/
https://www.ncbi.nlm.nih.gov/pubmed/27111843
http://dx.doi.org/10.1038/ncb3344

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