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Adapting SHIVs In Vivo Selects for Envelope-Mediated Interferon-α Resistance

Lentiviruses are able to establish persistent infection in their respective hosts despite a potent type-I interferon (IFN-I) response following transmission. A number of IFN-I-induced host factors that are able to inhibit lentiviral replication in vitro have been identified, and these studies sugges...

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Detalles Bibliográficos
Autores principales: Boyd, David F., Sharma, Amit, Humes, Daryl, Cheng-Mayer, Cecilia, Overbaugh, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939950/
https://www.ncbi.nlm.nih.gov/pubmed/27399306
http://dx.doi.org/10.1371/journal.ppat.1005727