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Exenatide Treatment Alone Improves β-Cell Function in a Canine Model of Pre-Diabetes

BACKGROUND: Exenatide’s effects on glucose metabolism have been studied extensively in diabetes but not in pre-diabetes. OBJECTIVE: We examined the chronic effects of exenatide alone on glucose metabolism in pre-diabetic canines. DESIGN AND METHODS: After 10 weeks of high-fat diet (HFD), adult dogs...

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Detalles Bibliográficos
Autores principales: Ionut, Viorica, Woolcott, Orison O., Mkrtchyan, Hasmik J., Stefanovski, Darko, Kabir, Morvarid, Iyer, Malini S., Liu, Huiwen, Castro, Ana V. B., Wu, Qiang, Broussard, Josiane L., Kolka, Cathryn M., Asare-Bediako, Isaac, Bergman, Richard N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939956/
https://www.ncbi.nlm.nih.gov/pubmed/27398720
http://dx.doi.org/10.1371/journal.pone.0158703