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Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside
This review covers the basic aspects of small interfering RNA delivery by lipid nano-particles (LNPs) and elaborates on the current status of clinical trials for these systems. We briefly describe the roles of all LNP components and possible strategies for their improvement. We also focus on the cur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939975/ https://www.ncbi.nlm.nih.gov/pubmed/27462152 http://dx.doi.org/10.2147/IJN.S106625 |