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Lipid nanoparticles for targeted siRNA delivery – going from bench to bedside

This review covers the basic aspects of small interfering RNA delivery by lipid nano-particles (LNPs) and elaborates on the current status of clinical trials for these systems. We briefly describe the roles of all LNP components and possible strategies for their improvement. We also focus on the cur...

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Detalles Bibliográficos
Autores principales: Zatsepin, Timofei S, Kotelevtsev, Yuri V, Koteliansky, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939975/
https://www.ncbi.nlm.nih.gov/pubmed/27462152
http://dx.doi.org/10.2147/IJN.S106625