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Rapamycin ameliorates CCl(4)-induced liver fibrosis in mice through reciprocal regulation of the Th17/Treg cell balance

Previous investigations have suggested that the activation of Th17 cells and/or deficiency of regulatory T cells (Tregs) are involved in the pathogenesis of liver fibrosis. The aim of the present study was to investigate the effect of rapamycin on immune responses in a carbon tetrachloride (CCl(4))-...

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Detalles Bibliográficos
Autores principales: Gu, Lei, Deng, Wen-Sheng, Sun, Xiao-Fei, Zhou, Hong, Xu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940054/
https://www.ncbi.nlm.nih.gov/pubmed/27315465
http://dx.doi.org/10.3892/mmr.2016.5392