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Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms

As a heat shock protein 90 inhibitor, 17-allyl-amino-17-demethoxygeldanamycin (17-AAG) has been studied in numerous types of cancer, however the effects of 17-AAG on apoptosis and the cell cycle of H446 cells remain unclear. In the current study, the MTT method was used to evaluate the inhibitory ef...

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Detalles Bibliográficos
Autores principales: Zhao, Xuerong, Wang, Jianping, Xiao, Lijun, Xu, Qian, Zhao, Enhong, Zheng, Xin, Zheng, Huachuan, Zhao, Shuang, Ding, Shi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940086/
https://www.ncbi.nlm.nih.gov/pubmed/27279418
http://dx.doi.org/10.3892/mmr.2016.5365