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Decreasing the ratio of matriptase/HAI-1 by downregulation of matriptase as a potential adjuvant therapy in ovarian cancer

Tumor invasion and metastasis are complex biological processes. Matriptase and its endogenous inhibitor, hepatocyte growth factor activator inhibitor-1 (HAI-1) are involved in invasion and metastasis. To evaluate the ratio of matriptase/HAI-1 and their potential therapeutic value in ovarian cancer,...

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Detalles Bibliográficos
Autores principales: Sun, Pengming, Jiang, Zhongqing, Chen, Xiaofang, Xue, Lifang, Mao, Xiaodan, Ruan, Guanyu, Song, Yiyi, Mustea, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940087/
https://www.ncbi.nlm.nih.gov/pubmed/27356668
http://dx.doi.org/10.3892/mmr.2016.5435