Rates and Mechanisms of Bacterial Mutagenesis from Maximum-Depth Sequencing

In 1943, Luria and Delbrück used a phage resistance assay to establish spontaneous mutation as a driving force of microbial diversity(1). Mutation rates are still studied using such assays, but these can only examine the small minority of mutations conferring survival in a particular condition. Newe...

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Detalles Bibliográficos
Autores principales: Jee, Justin, Rasouly, Aviram, Shamovsky, Ilya, Akivis, Yonatan, Steinman, Susan, Mishra, Bud, Nudler, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940094/
https://www.ncbi.nlm.nih.gov/pubmed/27338792
http://dx.doi.org/10.1038/nature18313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940094/
https://www.ncbi.nlm.nih.gov/pubmed/27338792
http://dx.doi.org/10.1038/nature18313

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