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Aspirin inhibits glucose-6-phosphate dehydrogenase activity in HCT 116 cells through acetylation: Identification of aspirin-acetylated sites

Glucose-6-phosphate dehydrogenase (G6PD) catalyzes the first reaction in the pentose phosphate pathway, and generates ribose sugars, which are required for nucleic acid synthesis, and nicotinamide adenine dinucleotide phosphate (NADPH), which is important for neutralization of oxidative stress. The...

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Detalles Bibliográficos
Autores principales: Ai, Guoqiang, Dachineni, Rakesh, Kumar, D. Ramesh, Alfonso, Lloyd F., Marimuthu, Srinivasan, Bhat, G. Jayarama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940102/
https://www.ncbi.nlm.nih.gov/pubmed/27356773
http://dx.doi.org/10.3892/mmr.2016.5449