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Secretion of protein disulphide isomerase AGR2 confers tumorigenic properties

The extracellular matrix (ECM) plays an instrumental role in determining the spatial orientation of epithelial polarity and the formation of lumens in glandular tissues during morphogenesis. Here, we show that the Endoplasmic Reticulum (ER)-resident protein anterior gradient-2 (AGR2), a soluble prot...

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Detalles Bibliográficos
Autores principales: Fessart, Delphine, Domblides, Charlotte, Avril, Tony, Eriksson, Leif A, Begueret, Hugues, Pineau, Raphael, Malrieux, Camille, Dugot-Senant, Nathalie, Lucchesi, Carlo, Chevet, Eric, Delom, Frederic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940162/
https://www.ncbi.nlm.nih.gov/pubmed/27240165
http://dx.doi.org/10.7554/eLife.13887