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A polyvalent influenza DNA vaccine applied by needle-free intradermal delivery induces cross-reactive humoral and cellular immune responses in pigs

BACKGROUND: Pigs are natural hosts for influenza A viruses, and the infection is widely prevalent in swine herds throughout the world. Current commercial influenza vaccines for pigs induce a narrow immune response and are not very effective against antigenically diverse viruses. To control influenza...

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Detalles Bibliográficos
Autores principales: Borggren, Marie, Nielsen, Jens, Karlsson, Ingrid, Dalgaard, Tina S., Trebbien, Ramona, Williams, James A., Fomsgaard, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940207/
https://www.ncbi.nlm.nih.gov/pubmed/27211039
http://dx.doi.org/10.1016/j.vaccine.2016.05.030