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A polyvalent influenza DNA vaccine applied by needle-free intradermal delivery induces cross-reactive humoral and cellular immune responses in pigs
BACKGROUND: Pigs are natural hosts for influenza A viruses, and the infection is widely prevalent in swine herds throughout the world. Current commercial influenza vaccines for pigs induce a narrow immune response and are not very effective against antigenically diverse viruses. To control influenza...
Autores principales: | Borggren, Marie, Nielsen, Jens, Karlsson, Ingrid, Dalgaard, Tina S., Trebbien, Ramona, Williams, James A., Fomsgaard, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940207/ https://www.ncbi.nlm.nih.gov/pubmed/27211039 http://dx.doi.org/10.1016/j.vaccine.2016.05.030 |
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