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FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2, and A...

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Detalles Bibliográficos
Autores principales: Zhao, Jonathan C., Fong, Ka-Wing, Jin, Hong-Jian, Yang, Yeqing A, Kim, Jung, Yu, Jindan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940300/
https://www.ncbi.nlm.nih.gov/pubmed/26751772
http://dx.doi.org/10.1038/onc.2015.496