Cargando…
FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression
Hormonal regulation of gene expression by androgen receptor (AR) is tightly controlled by many transcriptional cofactors, including pioneer factors FOXA1 and GATA2, which, however, exhibit distinct expression patterns and functional roles in prostate cancer. Here, we examined how FOXA1, GATA2, and A...
Autores principales: | Zhao, Jonathan C., Fong, Ka-Wing, Jin, Hong-Jian, Yang, Yeqing A, Kim, Jung, Yu, Jindan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940300/ https://www.ncbi.nlm.nih.gov/pubmed/26751772 http://dx.doi.org/10.1038/onc.2015.496 |
Ejemplares similares
-
GATA3 acts upstream of FOXA1 in mediating ESR1 binding by shaping enhancer accessibility
por: Theodorou, Vasiliki, et al.
Publicado: (2013) -
FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function
por: Yang, Yeqing A., et al.
Publicado: (2016) -
Current perspectives on FOXA1 regulation of androgen receptor signaling and prostate cancer
por: Yang, Yeqing Angela, et al.
Publicado: (2015) -
FOXA1 inhibits prostate cancer neuroendocrine differentiation
por: Kim, Jung, et al.
Publicado: (2017) -
Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours
por: Albergaria, André, et al.
Publicado: (2009)