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Conceptual convergence: increased inflammation is associated with increased basal ganglia glutamate in patients with major depression

Inflammation and altered glutamate metabolism are two pathways implicated in the pathophysiology of depression. Interestingly, these pathways may be linked given that administration of inflammatory cytokines such as interferon-α to otherwise non-depressed controls increased glutamate in the basal ga...

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Detalles Bibliográficos
Autores principales: Haroon, E, Fleischer, C C, Felger, J C, Chen, X, Woolwine, B J, Patel, T, Hu, X P, Miller, A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940313/
https://www.ncbi.nlm.nih.gov/pubmed/26754953
http://dx.doi.org/10.1038/mp.2015.206