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Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways

The cascade that culminates in macrometastases is thought to be mediated by phenotypic plasticity, including epithelial–mesenchymal and mesenchymal–epithelial transitions (EMT and MET). Although there is substantial support for the role of EMT in driving cancer cell invasion and dissemination, much...

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Detalles Bibliográficos
Autores principales: Somarelli, J A, Schaeffer, D, Marengo, M S, Bepler, T, Rouse, D, Ware, K E, Hish, A J, Zhao, Y, Buckley, A F, Epstein, J I, Armstrong, A J, Virshup, D M, Garcia-Blanco, M A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940344/
https://www.ncbi.nlm.nih.gov/pubmed/26751776
http://dx.doi.org/10.1038/onc.2015.497