Cargando…
Strong and Long-Lasting Antinociceptive and Anti-inflammatory Conjugate of Naturally Occurring Oleanolic Acid and Aspirin
The conjugate 8 was obtained as a result of condensation of 3-hydroxyiminooleanolic acid morfolide (7) and aspirin in dioxane. Analgesic effect of OAO-ASA (8) for the range of doses 0.3–300.0 mg/kg (p.o.) was performed in mice using a hot-plate test. Anti-inflammatory activity was assessed on carrag...
Autores principales: | Bednarczyk-Cwynar, Barbara, Wachowiak, Natalia, Szulc, Michal, Kamińska, Ewa, Bogacz, Anna, Bartkowiak-Wieczorek, Joanna, Zaprutko, Lucjusz, Mikolajczak, Przemyslaw L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940421/ https://www.ncbi.nlm.nih.gov/pubmed/27462270 http://dx.doi.org/10.3389/fphar.2016.00202 |
Ejemplares similares
-
Simple Amides of Oleanolic Acid as Effective Penetration Enhancers
por: Bednarczyk-Cwynar, Barbara, et al.
Publicado: (2015) -
The Effect of Oleanolic Acid and Its Four New Semisynthetic Derivatives on Human MeWo and A375 Melanoma Cell Lines
por: Bednarczyk-Cwynar, Barbara, et al.
Publicado: (2023) -
Biological Activity of Oleanolic Acid Derivatives HIMOXOL and Br-HIMOLID in Breast Cancer Cells Is Mediated by ER and EGFR
por: Lisiak, Natalia, et al.
Publicado: (2023) -
Recent advances in synthesis and biological activity of triterpenic acylated oximes
por: Bednarczyk-Cwynar, Barbara, et al.
Publicado: (2014) -
Oleanolic Acid’s Semisynthetic Derivatives HIMOXOL and Br-HIMOLID Show Proautophagic Potential and Inhibit Migration of HER2-Positive Breast Cancer Cells In Vitro
por: Lisiak, Natalia Magdalena, et al.
Publicado: (2021)