NF-κB1 Haploinsufficiency Causing Immunodeficiency and EBV-Driven Lymphoproliferation

PURPOSE: NF-κB signaling is critically important for regulation of both innate and adaptive immune responses. While activation of NF-κB has been implicated in malignancies such as leukemia and lymphoma, loss-of-function mutations affecting different NF-κB pathway components have been shown to cause...

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Detalles Bibliográficos
Autores principales: Boztug, Heidrun, Hirschmugl, Tatjana, Holter, Wolfgang, Lakatos, Karoly, Kager, Leo, Trapin, Doris, Pickl, Winfried, Förster-Waldl, Elisabeth, Boztug, Kaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940442/
https://www.ncbi.nlm.nih.gov/pubmed/27338827
http://dx.doi.org/10.1007/s10875-016-0306-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940442/
https://www.ncbi.nlm.nih.gov/pubmed/27338827
http://dx.doi.org/10.1007/s10875-016-0306-1

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