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NF-κB1 Haploinsufficiency Causing Immunodeficiency and EBV-Driven Lymphoproliferation
PURPOSE: NF-κB signaling is critically important for regulation of both innate and adaptive immune responses. While activation of NF-κB has been implicated in malignancies such as leukemia and lymphoma, loss-of-function mutations affecting different NF-κB pathway components have been shown to cause...
Autores principales: | Boztug, Heidrun, Hirschmugl, Tatjana, Holter, Wolfgang, Lakatos, Karoly, Kager, Leo, Trapin, Doris, Pickl, Winfried, Förster-Waldl, Elisabeth, Boztug, Kaan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940442/ https://www.ncbi.nlm.nih.gov/pubmed/27338827 http://dx.doi.org/10.1007/s10875-016-0306-1 |
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