Expression, purification and biological activity assessment of romiplostim biosimilar peptibody

BACKGROUND: Romiplostim is a peptibody analogue of thrombopoietin (TPO) which regulates platelet production. This molecule consists of two main parts: Peptide sequences which like wild type TPO, mimics stimulation of TPO receptor and IgG1Fc, (Peptide + Antibody = Peptibody). This drug is used in tre...

Descripción completa

Detalles Bibliográficos
Autores principales: Fayaz, Shima, Fard-Esfahani, Pezhman, Golkar, Majid, Allahyari, Mojgan, Sadeghi, Sedigheh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940717/
https://www.ncbi.nlm.nih.gov/pubmed/27401785
http://dx.doi.org/10.1186/s40199-016-0156-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940717/
https://www.ncbi.nlm.nih.gov/pubmed/27401785
http://dx.doi.org/10.1186/s40199-016-0156-7

Ejemplares similares