Cargando…

Expression, purification and biological activity assessment of romiplostim biosimilar peptibody

BACKGROUND: Romiplostim is a peptibody analogue of thrombopoietin (TPO) which regulates platelet production. This molecule consists of two main parts: Peptide sequences which like wild type TPO, mimics stimulation of TPO receptor and IgG1Fc, (Peptide + Antibody = Peptibody). This drug is used in tre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fayaz, Shima, Fard-Esfahani, Pezhman, Golkar, Majid, Allahyari, Mojgan, Sadeghi, Sedigheh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940717/ https://www.ncbi.nlm.nih.gov/pubmed/27401785 http://dx.doi.org/10.1186/s40199-016-0156-7

Ejemplares similares

Quality by Design in Downstream Process Development of Romiplostim
por: Pouri, Saeedeh, et al.
Publicado: (2022)

Expression and Purification of Recombinant ROP1 of Toxoplasma gondii in Bacteria
por: Mohabati, Reyhaneh, et al.
Publicado: (2013)

Efficacy and Safety of Biosimilar Romiplostim Versus Innovator Romiplostim in Patients with Chronic Immune Thrombocytopenia
por: Chandrakala, S., et al.
Publicado: (2022)

Correction to: Efficacy and Safety of Biosimilar Romiplostim Versus Innovator Romiplostim in Patients with Chronic Immune Thrombocytopenia
por: Chandrakala, S., et al.
Publicado: (2023)

Association of the Asp1312Gly Thyroglobulin Gene Polymorphism with Susceptibility to Differentiated Thyroid Cancer in an Iranian Population
por: Abidi, Maryam, et al.
Publicado: (2017)

Assessment of genetic mutations in the XRCC2 coding region by high resolution melting curve analysis and the risk of differentiated thyroid carcinoma in Iran
por: Fayaz, Shima, et al.
Publicado: (2012)

Bioengineered peptibodies as blockers of ion channels
por: Chidipi, Bojjibabu, et al.
Publicado: (2022)

Molecular identification of Phlebotomus kandelakii apyrase and assessment of the immunogenicity of its recombinant protein in BALB/c mice
por: Fayaz, Shima, et al.
Publicado: (2023)

A randomized, double‐blind, comparative study of the pharmacodynamics and pharmacokinetics of GP40141 (romiplostim biosimilar) and reference romiplostim in healthy male volunteers
por: Makarenko, Igor, et al.
Publicado: (2023)

High resolution melting assay in discrimination of the main etiologic agents of leishmaniasis in Iran
por: Fayaz, Shima, et al.
Publicado: (2021)

An overview of the sand fly salivary proteins in vaccine development against leishmaniases
por: Fayaz, Shima, et al.
Publicado: (2022)

Large‐scale production, purification, and function of a tumor multi‐epitope vaccine: Peptibody with bFGF/VEGFA
por: Zhang, Ligang, et al.
Publicado: (2020)

Immunoinformatics Evaluation of a Fusion Protein Composed of Leishmania infantum LiHyV and Phlebotomus kandelakii Apyrase as a Vaccine Candidate against Visceral Leishmaniasis
por: Fayaz, Shima, et al.
Publicado: (2022)

Development of a Quantitative Real-Time PCR Assay for Detection of Toxoplasma gondii in Brain Samples
por: Berizi, Mahboubeh, et al.
Publicado: (2021)

Development of Novel Promiscuous Anti-Chemokine Peptibodies for Treating Autoimmunity and Inflammation
por: Abraham, Michal, et al.
Publicado: (2017)

miR-1266-5p and miR-185-5p Promote Cell Apoptosis in Human Prostate Cancer Cell Lines
por: Ostadrahimi, Shiva, et al.
Publicado: (2018)

Assessment of immunogenicity of romiplostim in clinical studies with ITP subjects
por: Jawa, Vibha, et al.
Publicado: (2010)

The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA
por: Zhang, Ligang, et al.
Publicado: (2020)

Expression and Single-step Purification of GRA8 Antigen of Toxoplasma gondii in Escherichia coli
por: Babaie, Jalal, et al.
Publicado: (2011)

Romiplostim Treatment of Chemotherapy-Induced Thrombocytopenia
por: Soff, Gerald A., et al.
Publicado: (2019)

Retraction: The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA
Publicado: (2021)

Peptibody Based on FGFR1-Binding Peptides From the FGF4 Sequence as a Cancer-Targeting Agent
por: Jendryczko, Karolina, et al.
Publicado: (2021)

The role of romiplostim for pediatric patients with immune thrombocytopenia
por: Al-Samkari, Hanny, et al.
Publicado: (2020)

Romiplostim use in pregnant women with immune thrombocytopenia
por: Bussel, James B., et al.
Publicado: (2022)

Biologics and Biosimilars in Psoriasis
por: Ahmed, Sk Shahriar, et al.
Publicado: (2023)

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties
por: Sargis, Timothy, et al.
Publicado: (2022)

Romiplostim as early treatment of immune thrombocytopenia with severe immunodeficiency
por: Palandri, Francesca, et al.
Publicado: (2012)

Romiplostim as a treatment for immune thrombocytopenia: a review
por: Chalmers, Sarah, et al.
Publicado: (2015)

Role of romiplostim in splenectomized and nonsplenectomized patients with immune thrombocytopenia
por: Perdomo, Jose
Publicado: (2016)

Thrombopoietin mutation in congenital amegakaryocytic thrombocytopenia treatable with romiplostim
por: Pecci, Alessandro, et al.
Publicado: (2017)

A Review of Romiplostim Mechanism of Action and Clinical Applicability
por: Bussel, James B, et al.
Publicado: (2021)

Drug Conjugation via Maleimide–Thiol Chemistry Does Not Affect Targeting Properties of Cysteine-Containing Anti-FGFR1 Peptibodies
por: Jendryczko, Karolina, et al.
Publicado: (2022)

Assessment of romiplostim immunogenicity in adult patients in clinical trials and in a global postmarketing registry
por: Mytych, Daniel T., et al.
Publicado: (2020)

Assessment of romiplostim immunogenicity in pediatric patients in clinical trials and in a global postmarketing registry
por: Bowers, Charles, et al.
Publicado: (2021)

Circulating miR-20a and miR-26a as Biomarkers in Prostate Cancer
por: Torbati, Peyman Mohammadi, et al.
Publicado: (2019)

FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
por: Jendryczko, Karolina, et al.
Publicado: (2020)

Myelofibrosis Associated with Romiplostim Treatment in a Patient with Immune Thrombocytopenia
por: Gonzalez, Maria Fernanda, et al.
Publicado: (2012)

Cost Effectiveness of Romiplostim for the Treatment of Chronic Immune Thrombocytopenia in Ireland
por: Lee, Dawn, et al.
Publicado: (2013)

Romiplostim for the Emergency Management of Severe Immune Thrombocytopenia with Intracerebral Hemorrhage
por: Gellens, Romain, et al.
Publicado: (2018)

Long-term safety and efficacy of romiplostim for treatment of immune thrombocytopenia
por: Vishnu, Prakash, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1n39nbniho247b35grdkc8l213