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Development of a synthetic gene network to modulate gene expression by mechanical forces

The majority of (mammalian) cells in our body are sensitive to mechanical forces, but little work has been done to develop assays to monitor mechanosensor activity. Furthermore, it is currently impossible to use mechanosensor activity to drive gene expression. To address these needs, we developed th...

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Detalles Bibliográficos
Autores principales: Kis, Zoltán, Rodin, Tania, Zafar, Asma, Lai, Zhangxing, Freke, Grace, Fleck, Oliver, Del Rio Hernandez, Armando, Towhidi, Leila, Pedrigi, Ryan M., Homma, Takayuki, Krams, Rob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940741/
https://www.ncbi.nlm.nih.gov/pubmed/27404994
http://dx.doi.org/10.1038/srep29643