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Development of a synthetic gene network to modulate gene expression by mechanical forces
The majority of (mammalian) cells in our body are sensitive to mechanical forces, but little work has been done to develop assays to monitor mechanosensor activity. Furthermore, it is currently impossible to use mechanosensor activity to drive gene expression. To address these needs, we developed th...
Autores principales: | Kis, Zoltán, Rodin, Tania, Zafar, Asma, Lai, Zhangxing, Freke, Grace, Fleck, Oliver, Del Rio Hernandez, Armando, Towhidi, Leila, Pedrigi, Ryan M., Homma, Takayuki, Krams, Rob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940741/ https://www.ncbi.nlm.nih.gov/pubmed/27404994 http://dx.doi.org/10.1038/srep29643 |
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