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Effect of 12-O-tetradecanoylphorbol-13-acetate-induced psoriasis-like skin lesions on systemic inflammation and atherosclerosis in hypercholesterolaemic apolipoprotein E deficient mice

BACKGROUND: Risk of cardiovascular disease is increased in patients with psoriasis, but molecular mechanisms linking the two conditions have not been clearly established. Lack of appropriate animal models has hampered generation of new knowledge in this area of research and we therefore sought to de...

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Detalles Bibliográficos
Autores principales: Madsen, Marie, Hansen, Peter Riis, Nielsen, Lars Bo, Hartvigsen, Karsten, Pedersen, Anders Elm, Christensen, Jan Pravsgaard, Aarup, Annemarie, Pedersen, Tanja Xenia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940745/
https://www.ncbi.nlm.nih.gov/pubmed/27401543
http://dx.doi.org/10.1186/s12895-016-0046-1