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A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies

BACKGROUND: Pancreatic cancer is one of the most lethal of human malignancies known to date and shows relative insensitivity towards most of the clinically available therapy regimens. 3,5-bis(2-fluorobenzylidene)-4-piperidone (EF24), a novel synthetic curcumin analog, has shown promising in vitro th...

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Detalles Bibliográficos
Autores principales: Bisht, Savita, Schlesinger, Martin, Rupp, Alexander, Schubert, Rolf, Nolting, Jens, Wenzel, Jörg, Holdenrieder, Stefan, Brossart, Peter, Bendas, Gerd, Feldmann, Georg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940769/
https://www.ncbi.nlm.nih.gov/pubmed/27401816
http://dx.doi.org/10.1186/s12951-016-0209-6