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Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice

BACKGROUND: Trigeminal nerve damage-induced neuropathic pain is a severely debilitating chronic orofacial pain syndrome. Spinal chemokine CXCL13 and its receptor CXCR5 were recently demonstrated to play a pivotal role in the pathogenesis of spinal nerve ligation-induced neuropathic pain. Whether and...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Cao, De-Li, Zhang, Zhi-Jun, Jiang, Bao-Chun, Gao, Yong-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940825/
https://www.ncbi.nlm.nih.gov/pubmed/27401148
http://dx.doi.org/10.1186/s12974-016-0652-1