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Chemokine CXCL13 mediates orofacial neuropathic pain via CXCR5/ERK pathway in the trigeminal ganglion of mice
BACKGROUND: Trigeminal nerve damage-induced neuropathic pain is a severely debilitating chronic orofacial pain syndrome. Spinal chemokine CXCL13 and its receptor CXCR5 were recently demonstrated to play a pivotal role in the pathogenesis of spinal nerve ligation-induced neuropathic pain. Whether and...
Autores principales: | Zhang, Qian, Cao, De-Li, Zhang, Zhi-Jun, Jiang, Bao-Chun, Gao, Yong-Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940825/ https://www.ncbi.nlm.nih.gov/pubmed/27401148 http://dx.doi.org/10.1186/s12974-016-0652-1 |
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