Transcriptome sequencing reveals that LPS-triggered transcriptional responses in established microglia BV2 cell lines are poorly representative of primary microglia

BACKGROUND: Microglia are resident myeloid cells in the CNS that are activated by infection, neuronal injury, and inflammation. Established BV2 microglial cell lines have been the primary in vitro models used to study neuroinflammation for more than a decade because they reduce the requirement of co...

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Detalles Bibliográficos
Autores principales: Das, Amitabh, Kim, Sun Hwa, Arifuzzaman, Sarder, Yoon, Taeho, Chai, Jin Choul, Lee, Young Seek, Park, Kyoung Sun, Jung, Kyoung Hwa, Chai, Young Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940985/
https://www.ncbi.nlm.nih.gov/pubmed/27400875
http://dx.doi.org/10.1186/s12974-016-0644-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4940985/
https://www.ncbi.nlm.nih.gov/pubmed/27400875
http://dx.doi.org/10.1186/s12974-016-0644-1

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