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Induction of differentiation in psoriatic keratinocytes by propylthiouracil and fructose()
Psoriasis is characterized by uncontrolled proliferation and poor differentiation. Sirtuin1 (SIRT1) a class III deacetylase, crucial for differentiation in normal keratinocytes, is reduced in psoriasis. Down regulated SIRT1 levels may contribute to poor differentiation in psoriasis. In addition, the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941040/ https://www.ncbi.nlm.nih.gov/pubmed/27453822 http://dx.doi.org/10.1016/j.bbacli.2016.06.002 |