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The mechanical response of talin

Talin, a force-bearing cytoplasmic adapter essential for integrin-mediated cell adhesion, links the actin cytoskeleton to integrin-based cell–extracellular matrix adhesions at the plasma membrane. Its C-terminal rod domain, which contains 13 helical bundles, plays important roles in mechanosensing d...

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Detalles Bibliográficos
Autores principales: Yao, Mingxi, Goult, Benjamin T., Klapholz, Benjamin, Hu, Xian, Toseland, Christopher P., Guo, Yingjian, Cong, Peiwen, Sheetz, Michael P., Yan, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941051/
https://www.ncbi.nlm.nih.gov/pubmed/27384267
http://dx.doi.org/10.1038/ncomms11966