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Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination

Synaptic inhibition in the olfactory bulb (OB), the first relay station of olfactory information, is believed to be important for odour discrimination. We interfered with GABAergic inhibition of mitral and tufted cells (M/T cells), the principal neurons of the OB, by disrupting their potassium-chlor...

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Detalles Bibliográficos
Autores principales: Gödde, Kathrin, Gschwend, Olivier, Puchkov, Dmytro, Pfeffer, Carsten K., Carleton, Alan, Jentsch, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941119/
https://www.ncbi.nlm.nih.gov/pubmed/27389623
http://dx.doi.org/10.1038/ncomms12043