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Aliskiren Administration during Early Postnatal Life Sex-Specifically Alleviates Hypertension Programmed by Maternal High Fructose Consumption

Key points summary: Maternal high-fructose (HF) induces programmed hypertension in adult offspring. Early aliskiren administration prevents HF-induced hypertension in both sexes of adult offspring. HF regulates RAS components in the offspring kidney in a sex-specific manner. HF alters renal transcri...

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Detalles Bibliográficos
Autores principales: Hsu, Chien-Ning, Wu, Kay L. H., Lee, Wei-Chia, Leu, Steve, Chan, Julie Y. H., Tain, You-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941125/
https://www.ncbi.nlm.nih.gov/pubmed/27462279
http://dx.doi.org/10.3389/fphys.2016.00299