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Loss of histone variant macroH2A2 expression associates with progression of anal neoplasm

AIMS: The macroH2A histone variants are epigenetic marks for inactivated chromatin. In this study, we examined the expression of macroH2A2 in anal neoplasm from anal intraepithelial neoplasia (AIN) to anal squamous cell carcinoma (SCC). METHODS: AIN and anal SCC samples were analysed for macroH2A2 e...

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Detalles Bibliográficos
Autores principales: Hu, Wan-Hsiang, Miyai, Katsumi, Sporn, Judith C, Luo, Linda, Wang, Jean Y J, Cosman, Bard, Ramamoorthy, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941135/
https://www.ncbi.nlm.nih.gov/pubmed/26658220
http://dx.doi.org/10.1136/jclinpath-2015-203367